Abstract #2372
Fast Sodium MRI of the Human Brain Using a Balanced Steady-State Free Precession Sequence
Ruomin Hu 1 , Simon Konstandin 2 , and Lothar R. Schad 1
1
Computer Assisted Clinical Medicine,
Heidelberg University, Mannheim, Baden-Wrttemberg,
Germany,
2
MR-Imaging
and Spectroscopy, University of Bremen, Bremen, Bremen,
Germany
Sodium magnetic resonance imaging sets its focus of
research primarily on the measurement of tissue sodium
concentration with the attempt to distinguish between
intra- and extracellular space. An alternative is
represented by sodium imaging exhibiting
relaxation-based contrast. The main goal of this work is
to develop a sequence to explore the feasibility and
properties of relaxation-based sodium imaging using
phantoms as well as in vivo. Structural changes of the
macromolecular environment such as the demyelination of
axons and the degradation of cartilage might be
highlighted using this contrast-generating technique.
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