Abstract #2316
Injury alters the intrinsic functional connectivity network in spinal cord of monkeys
Li Min Chen 1,2 , Arabinda Mishra 1,2 , Feng Wang 1,2 , Pai-Feng Yang 1,2 , and John C. Gore 1,2
1
Radiology and Radiological Sciences,
Vanderbilt University, Nashville, TN, United States,
2
Institute
of Imaging Science, Vanderbilt University, Nashville,
TN, United States
Resting state fMRI has shown that intrinsic functional
connectivity networks may be detected in the spinal cord
of humans and anesthetized monkeys. The functional
relevance of these networks, however, remains to be
determined. One way to address this question is to
modulate the network and then correlate the changes with
behavioral and functional outcomes. In this study we
examined the effects of unilateral spinal cord injury on
the inter-regional correlation strengths of resting
state fMRI signals between spinal horns of gray matter
in spinal segments above or below the injury level.
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