Abstract #2306
Measurement of the Vitreous Humour Deformation and Strain with Tagged MR Imaging
Ming Li 1,2 , Paul Gamlin 3 , Mark S. Bolding 4,5 , Ronald J. Beyers 1 , Nouha Salibi 1,6 , Xiaoxia Zhang 1,2 , and Thomas S. Denney Jr. 1,2
1
Auburn University MRI Research Center,
Auburn University, Auburn, AL, United States,
2
Electrical
and Computer Engineering, Auburn University, Auburn, AL,
United States,
3
Department of Ophthalmology,
University of Alabama at Birmingham, Birmingham, AL,
United States,
4
Departments
of Radiology, Vision Sciences, and Neurobiology,
University of Alabama at Birmingham, Birmingham, AL,
United States,
5
Civitan
Functional Neuroimaging Laboratory, University of
Alabama at Birmingham, Birmingham, AL, United States,
6
MR
R&D, Siemens Healthcare, Malvern, PA, United States
The vitreous humour undergoes mechanical changes that
are thought to be related to a range of pathologies
including retinal detachment and are reflected on the
motion pattern of the vitreous humour during eye
movements. We analyzed the in-vivo dynamics of the
vitreous humour under smooth pursuit eye movement, using
tagged MRI with a standard head coil in a 7 Tesla
scanner. We also propose a method for measuring regional
shear strain in the vitreous humour, which does not use
assumptions on the geometry of the globe or material
properties of the vitreous.
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