Abstract #2291
Diffusion tensor imaging of the auditory nerve in patients with long-term single-sided deafness
Sjoerd B Vos 1,2 , Wieke Haakma 3,4 , Huib Versnel 1 , Martijn Froeling 3 , Lucienne Speleman 1 , Pieter Dik 5 , Max A Viergever 2 , Alexander Leemans 2 , and Wilko Grolman 1
1
Department of Otorhinolaryngology and Head &
Neck Surgery, University Medical Center Utrecht,
Utrecht, Netherlands,
2
Image
Sciences Institute, University Medical Center Utrecht,
Utrecht, Netherlands,
3
Department
of Radiology, University Medical Center Utrecht,
Utrecht, Netherlands,
4
Department
of Forensic Medicine & Comparative Medicine Lab, Aarhus
University, Denmark,
5
Department
of Pediatric Urology, University Children's Hospital UMC
Utrecht, Utrecht, Netherlands
The viability of the auditory nerve in deaf patients is
critical in hearing recovery after cochlear implantation
(CI). The nerve degenerates following cochlear hair cell
loss and the amount of degeneration varies between ears.
DTI may yield a measure of nerve degeneration by
allowing noninvasive estimates of the nerves
microstructure. We show the first use of DTI to image
the auditory nerve using a specialized acquisition
protocol on a clinical 3T scanner. Our results show a
bilateral decrease in FA in unilaterally deaf patients
compared to normal-hearing controls. No differences were
observed between the deaf and healthy-sided nerves in
patients.
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