Abstract #2288
Effectively Improving Accuracy and Reliability in Intracranial Volume Change for MR Intracranial Pressure Measurement
Yi-Hsin Tsai 1 , Hung-Chieh Chen 2 , Hsin Tung 3 , Da-Chuan Cheng 4 , Clayton Chi-Chang Chen 2 , Jyh-Wen Chai 1,2 , Hsiao-Wen Chung 5 , and Wu-Chung Shen 6
1
College of Medicine, China Medical
University, Taichung, Taichung, Taiwan,
2
Department
of Radiology, Taichung Veterans General Hospital,
Taichung, Taichung, Taiwan,
3
Neurological
Institute, Taichung Veterans General Hospital, Taiwan,
Taiwan,
4
Department
of Biomedical Imaging and Radiological Science, China
Medical University, Taichung, Taichung, Taiwan,
5
Department
of Electrical Engineering, National Taiwan University,
Taipei, Taiwan,
6
College
of Health Care, China Medical University, Taichung,
Taichung, Taiwan
Non-invasive MR intracranial pressure measurement (MR-ICP)
has limited clinical applicability due to measurement
errors, a great portion of which likely comes from
internal jugular vein (IJV) pulsations. Experiments on
normal volunteers were conducted to evaluate how the IJV
flow patterns on various measurement positions affect
the peak-to-peak intracranical volume changes (ICVC),
which then used to estimate the MR-ICP. Results showed
strong correlations between ICVC and IJV pulsatility
indexes, both increasing as slices caudally shifted,
quite apparently caused by right atrial hemodynamics.
With properly positioned IJV measurement, the accuracy
and reliability of MR-ICP measurement can be effectively
improved.
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