Abstract #2188
Susceptibility-weighted imaging of acute ischemic stroke: quantification of hypoperfusion
Hung-Wen Kao 1,2 , Yu-Chuan Chang 3 , Ching-Po Lin 2,4 , and Chien-Yuan Eddy Lin 5,6
1
Department of Radiology, Tri-Service General
Hospital, National Defense Medical Center, Taipei,
Taiwan,
2
Department
of Biomedical Imaging and Radiological Sciences,
National Yang-Ming University, Taipei, Taiwan,
3
Graduate
Institute of Biomedical Electronics and Bioinformatics,
National Taiwan University, Taipei, Taiwan,
4
Institute
of Neuroscience, National Yang-Ming University, Taipei,
Taiwan,
5
GE
Healthcare, Taipei, Taiwan,
6
GE
Healthcare China, Beijing, China
Susceptibility-weighted imaging (SWI) is very sensitive
in detecting blood products and showing
blood-oxygen-level dependent (BOLD) signal changes
presumably from different concentrations of deoxygenated
blood. Therefore, we hypothesize that SWI could provide
oxygen metabolic information in relation to perfusion in
patients with acute ischemic stroke. In our study, we
compared area percentages of increased BOLD signal (IBS)
in ROIs of restricted diffusion and perfusion defect.
The results suggested a positive correlation between
perfusion and IBS, a finding contradicting the
implication of IBS as miserable perfusion and indicating
a mismatch between perfusion and oxygen metabolism.
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