Abstract #2047
Whole-brain, sub-second data collection for task-evoked fMRI studies using simultaneous multi-slice/multiband acquisition
Stephanie McMains 1 , R Matthew Hutchison 1,2 , and Ross W Mair 1,3
1
Center for Brain Science, Harvard
University, Cambridge, MA, United States,
2
Department
of Psychology, Harvard University, Cambridge, MA, United
States,
3
AA
Martinos Center for Biomedical Imaging, Massachusetts
General Hospital, Charlestown, MA, United States
We studied visual cortex response at a variety of slice
accelerations and TR reductions to investigate the
advantages and potential costs for task-based fMRI
associated with parameters that allow for whole-brain,
sub-second data collection with both block and
event-related design paradigms. tstats were
significantly higher in the block-design short-TR scans,
due to the much larger number of time-points acquired.
However, a significant increase is still observed after
auto-regressive modeling correction, indicating benefits
to block-design experiments from high temporal
resolution acquisitions. The observation of higher betas
in the event-related design experiment with the short-TR
scans is unexpected, and perhaps indicates the
hemodynamic response is captured more accurately with
the higher temporal resolution.
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