Abstract #1996
B 0 insensitive biexponentially weighted 23 Na imaging
Nadia Benkhedah 1 and Armin M. Nagel 1
1
Medical Physics in Radiology, German Cancer
Research Center (DKFZ), Heidelberg, Germany
The intracellular sodium concentration is of great
interest since it is a potential measure for small
changes of the sodium ion homeostasis. Methods which
allow a weighting toward intracellular sodium are based
on the generation a weighted subtraction image and are
thus highly influenced by inhomogeneities of the
magnetic field. In the two pulse sequence two different
pathways contribute to the long echo time image, so
destructive interference can also lead to signal voids
in regions prone to field inhomogeneities. In this
study, the pathways of the two pulse sequence have been
acquired separately to obtain an intracellular weighted
23
Na
image which is more robust to variations in the main
magnetic field.
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