Abstract #1751
Spiral-CEST Encoding with Spectral and Spatial B0 Correction
Sugil Kim 1,2 and Jaeseok Park 3
1
Department of Brain and Cognitive
Engineering, Korea University, Seoul, Korea,
2
Center
for Neuroscience Imaging Research, Institute for Basic
Science (IBS), Sungkyunkwan University, Suwon, Korea,
3
Biomedical
Imaging and Engineering Lab., Department of Global
Biomedical Engineering, Sungkyunkwan University, Suwon,
Korea
Chemical exchange saturation transfer (CEST), which
exploits saturation transfer induced proton exchange and
its corresponding, indirect loss of water signals, has
been shown to provide a novel contrast mechanism in MRI
[1,2]. However, CEST MRI is highly vulnerable to
magnetic field inhomogeneities. To address this problem,
it often requires multi-spectral acquisitions
(z-spectrum), and hence leads to prohibitively long
imaging time [3]. In this work, we propose Spiral-CEST
encoding with spectral and spatial B0 correction under
the hypothesis that in the presence of magnetic field
inhomogeneities spiral encoding induced image blurring
in the spatial dimension makes no contribution to a DC
frequency shift in the z-spectral dimension due to the
spatially, slowly varying field map.
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