Abstract #1741
B 1 -Sensitivity Analysis of qMT
Mathieu Boudreau 1 , Nikola Stikov 1 , and G. Bruce Pike 2
1
McConnell Brain Imaging Center, Montreal
Neurological Institute, McGill University, Montreal,
Quebec, Canada,
2
Hotchkiss
Brain Institute, Faculty of Medicine, University of
Calgary, Calgary, Alberta, Canada
B
1
mapping
is an important measurement used in qMT imaging. For
pulsed SPGR qMT imaging experiments, B
1
maps
are used as a corrective factor for the excitation flip
angle and MT saturation. Inaccuracies in B
1
mapping
will propagate to the fitted qMT parameters differently,
depending on the B
1
-dependence of the T
1
mapping
method. Here we present a simulation-based analysis of
the B
1
-sensitivity of qMT, comparing how
different T
1
mapping
methods (VFA, IR) propagate the B
1
error
to the qMT parameters. We show that the pool-size ratio
F is very robust to B
1
inaccuracies
for VFA, as opposed to IR.
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