Abstract #1654
High speed, high sensitivity MR thermometry using a balanced steady-state free precession pulse sequence
Yuan Zheng 1 and G. Wilson Miller 2
1
Physics, University of Virginia,
Charlottesville, VA, United States,
2
Radiology
and Medical Imaging, University of Virginia,
Charlottesville, VA, United States
We have developed a proton resonance frequency shift (PRFS)
based MR thermometry technique that collects
temperature-sensitive phase images using a balanced
steady-state free precession (bSSFP) pulse sequence. Our
technique makes use of the sharp phase transition of
bSSFP images over a narrow frequency range near
resonance. Although the phase transition is non-linear,
the phase change can be accurately mapped to PRFS (and
thus temperature) using a pre-scanned phase transition
curve. We performed phantom experiments using MR-guided
focused ultrasound, to demonstrate the advantages of our
bSSFP technique over conventional GRE-based methods for
measuring small, fast temperature changes at the
ultrasound focus.
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