Abstract #1626
Improved retinal shape detection using high-resolution MRI compared to partial coherence interferometry
Jan-Willem M Beenakker 1,2 , Mihai State 3 , Denis P Shamonin 4 , Marrie van der Mooren 3 , Berend C Stoel 4 , Andrew G Webb 1 , Gregorius PM Luyten 2 , and Patricia Piers 3
1
Department of Radiology, C.J.Gorter Center
for High Field MRI, Leiden University Medical Center,
Leiden, Zuid-Holland, Netherlands,
2
Department
of Ophthalmology, Leiden University Medical Center,
Leiden, Zuid-Holland, Netherlands,
3
AMO
Groningen BV, Groningen, Netherlands,
4
Department
of Radiology, devision of Image Processing, Leiden
University Medical Center, Leiden, Zuid-Holland,
Netherlands
Current techniques in ophthalmology, such as PCI
(partial coherence interferometry), cannot accurately
measure the retinal shape because refraction causes
systematic errors for off-axis measurements. We assessed
these errors by measuring the left eye of 16 volunteers
using high-resolution ocular MRI, which is not
influenced by refraction, and PCI. The on-axis data
shows the high accuracy of ocular MRI (systematic error
0.08mm), while off-axis measurements show large
systematic differences between the techniques. This
shows the importance of MRI as the gold-standard for
three-dimensional retinal shape characterisation.
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