Abstract #1602
Clinical feasibility of time-dependent diffusion MRI for improved prostate cancer grading
Gregory Lemberskiy 1,2 , Dmitry S Novikov 1 , Henry Rusinek 1 , Els Fieremans 1 , and Andrew Rosenkrantz 1
1
Bernard and Irene Schwartz Center for
Biomedical Imaging, Department of Radiology, New York
University School of Medicine, New York, NY, United
States,
2
Sackler
Institute of Graduate Biomedical Sciences, New York
University School of Medicine, New York, NY, United
States
Synopsis: Time-dependent diffusion can be used to
distinguish populations of low grade/high grade and
benign tissue in prostate tissue. We found that
peripheral zone experiences transient time-dependence,
while tumors have a constant dependence in the same
range. Adding time-dependent ADC acquisitions for such
analysis is clinically feasible as it costs ~7 minutes
without the use of state of the art acceleration
techniques.
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