Abstract #1584
Urinary 1 H NMR-based Metabolomics can Distinguish Sub-fertility Buffalo Bulls
Virendra Kumar 1 , Pawan Kumar 1 , Khushpreet Singh 2 , N R Jagannaathan 1 , and Ajeet Kumar 2
1
Department of NMR, All India Institute of
Medical Sciences, New Delhi, Delhi, India,
2
Department
of Veterinary Gynaecology and Obstetrics, College of
Veterinary Science, GADVASU, Ludhiana, Punjab, India
Sub-fertility in bulls is a major problem and results
into huge economic loss. Identification of potential
metabolic biomarkers to determine the fertility at
earlier developmental stage accurately is important. In
present study we used
1
H
NMR-based metabolomics to investigate the metabolic
profile differences in urine samples to differentiate
between buffalo bulls of good fertility and poor
fertility. The results of the PLS-DA revealed that
sub-fertile bulls be differentiated from fertile bulls
based on altered urinary metabolic profiles. Further
analysis will be carried out to identify potential
metabolic biomarkers which could be used for fertility
assessment.
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