Abstract #1520
Intravoxel incoherent motion diffusion-weighted imaging and texture heterogeneity for staging of hepatic fibrosis in children
WEIMIN AN 1 , JING ZHANG 2 , and HUI XIE 1
1
department of radiology, 302 military
hospital of china, Beijing, Beijing, China,
2
GE
Healthcare China, Beijing, China
Diffusion weighted imaging (DWI) has been used to assess
liver fibrosis by mean apparent diffusion coefficient
values in liver parenchyma. However, fibrotic
distribution in the liver is progressive and uneven, and
the ADC value can be influenced by true molecular
diffusion in a solid tissue and microcirculation in
vessels , which limit the general utility of
conventional DWI. With the advent of intravoxel
incoherent motion (IVIM) mode, perfusion-related
diffusivity and pure molecular diffusivity could be
generalized simultaneously. We therefore assessed
performance of IVIM DWI parameters and corresponding
coefficients of variation (CVs) for liver fibrotic
staging and texture heterogeneity analysis in children.
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