Abstract #1516
Feasibility of MR Elastography of the Liver in Obese Patients at Risk for NAFLD
Curtis N Wiens 1 , Alan B McMillan 1 , Nathan S Artz 1,2 , Rashmi Agni 3 , Nikolaus Szeverenyi 4 , William Haufe 4 , Catherine Hooker 4 , Meng Yin 5 , Guilherme M Campos 6 , Claude Sirlin 4 , and Scott B Reeder 1,7
1
Department of Radiology, University of
Wisconsin, Madison, Wisconsin, United States,
2
Department
of Radiological Sciences, St. Jude Children's Research
Hospital, Memphis, Tennessee, United States,
3
Department
of Pathology, University of Wisconsin, Madison,
Wisconsin, United States,
4
Department
of Radiology, University of California, San Diego,
California, United States,
5
Department
of Radiology, Mayo Clinic, Rochester, Minnesota, United
States,
6
Department
of Surgery, University of Wisconsin, Madison, Wisconsin,
United States,
7
Department
of Medical Physics, University of Wisconsin, Madison,
Wisconsin, United States
This study demonstrated feasibility of hepatic MR
elastography (MRE) in obese patients. 54 patients (BMI:
456 kg/m2) undergoing bariatric surgery were recruited
for a hepatic MR examination including MRE and fat
quantification. Hepatic stiffness measurements from MRE
were compared to fibrosis stage obtained from
intraoperative liver biopsies. The tech-nical success
rate of MRE in this population was 81%. MRE quality was
adversely affected by greater subcutaneous adi-pose
tissue thickness, smaller voxel size, and greater
hepatic fat fraction.
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