Abstract #1481
How volume affects the pulmonary MRI signal: Investigations with 3D ultra-fast balanced Steady-State Free Precession
Orso Pusterla 1 , Oliver Bieri 1 , Gregor Sommer 2 , and Grzegorz Bauman 1
1
Radiological Physics, Department of
Radiology, University of Basel Hospital, Basel,
Switzerland,
2
Clinic
of Radiology and Nuclear Medicine, Department of
Radiology, University of Basel Hospital, Basel,
Switzerland
3D ultra-fast balanced Steady-State Free Procession
imaging - originally suggested for improved
morphological chest imaging and visualization of the
lung parenchyma and vasculature - was used for exploring
the functional dependence between the pulmonary MRI
signal and the lung's volume in healthy volunteers. It
is demonstrated that the signal intensity in healthy
volunteers can be empirically described by a non-linear
function that scales inversely proportional with the
lung volume. The suggested experimental protocol may be
beneficial for patients with respiratory diseases, where
a distorted signal intensity dependence on the lung
volume may reflect pathological changes of the lung
parenchyma.
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