Abstract #1469
3D Ultrashort TE (UTE) MRI repeatability within the thorax and its application to pulmonary fibrosis.
Alexander Weller 1 , Sharon L Giles 2 , Veronica A Morgan 2 , David Collins 1 , David M Higgins 3 , and Nandita M de-Souza 1
1
CRUK Cancer Imaging Centre, Institute of
Cancer Research, Sutton, Surrey, United Kingdom,
2
MRI
Department, Royal Marsden Hospital, Sutton, Surrey,
United Kingdom,
3
Clinical
Science, Philips Healthcare, Guildford, Surrey, United
Kingdom
T2* quantification within lung parenchyma using
Ultra-short time to echo (UTE) MRI has previously been
shown to correlate with pulmonary fibrosis in mice and
CT density in humans. Here, T2* values are reported for
patients with lung carcinoma, from MRI studies performed
pre and post radiotherapy. Repeatability of T2* values
within tumor and surrounding lung are confirmed before
demonstrating: (a) T2* values for fibrotic lung and; (b)
change in T2* following radiotherapy. The results
reflect the potential for UTE MRI in both early
identification of pulmonary fibrosis and in
differentiating fibrosis from pneumonitis on CT.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
