Abstract #1446
The impact of fluctuated tCBF induced by cardiac pulsation on the global CMRO2 measurement
Chou-Ming Cheng 1,2 , Hsiao-Wen Chung 2 , Jen-Chuen Hsieh 1,3 , Shing-Jong Lin 1 , and Tzu-Chen Yeh 3,4
1
Department of Medical Research, Taipei
Veterans General Hospital, Taipei, Taiwan, Taiwan,
2
Graduate
Institute of Biomedical Electronics and Bioinformatics,
National Taiwan University, Taiwan, Taiwan,
3
Institute
of Brain Science, National Yang-Ming University, Taiwan,
Taiwan,
4
Department
of Radiology, Taipei Veterans General Hospital, Taiwan,
Taiwan
Recently, the total cerebral blood flow (tCBF) and
venous oxygen saturation (SvO2) levels are measured
noninvasively with the MRI approaches to quantify the
global cerebral metabolic rate of oxygen (CMRO2). In
this research, the ROI analysis with the cardiac gating
sequence is applied in healthy subjects to demonstrate
the impact of fluctuated tCBF induced by cardiac
pulsation on the global CMRO2 measurement.
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