Abstract #1431
Suppression of streak artifacts in quantitative susceptibility mapping
Wen-Tung Wang 1 , Dzung Pham 1 , and John A Butman 1,2
1
Center for Neuroscience and Regenerative
Medicine, Bethesda, MD, United States,
2
Radiology
and Imaging Sciences, National Institutes of Health,
Bethesda, MD, United States
Quantitative Susceptibility Mapping (QSM) offers unique,
quantitative information about the magnetic
susceptibility of tissues. While multi-orientation QSM
can faithfully reconstruct susceptibility maps, it is
computationally demanding and impractical for clinical
scans. Single-orientation QSMs mitigate computational
load and patient discomfort, but streak artifacts in
susceptibility maps may still appear due to mathematical
approximations. We propose to apply the
single-orientation QSM twice, one at chin-up and the
other chin-down orientation, using fast 3D segmented EPI
to reduce streak artifacts while maintaining accuracy of
the susceptibility measurements. The average of the two
orientations substantially eliminates the artifacts as
compared to a single orientation.
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