Abstract #1413
Longitudinal Analysis of Structural and Functional Connectivity of the Thalamus and Anterior Cingulate Cortex in Mild Traumatic Brain Injury
Armin Iraji 1 , Natalie Wiseman 1 , Robert Welch 1 , Brian O'Neil 1 , Andrew Kulek 1 , Syed Imran Ayaz 1 , E Mark Haacke 1 , and Zhifeng Kou 1
1
Wayne State University, Detroit, Michigan,
United States
Mild traumatic brain injury (mTBI) is a significant
public healthcare burden that costs the nation billions
of dollars each year. Most mTBI patients have normal
findings in clinical neuroimaging; however, there are
several cognitive and emotional symptoms that can impact
patients quality of life. Therefore, we expected to see
changes in brain regions associated with higher order
functions. The thalamus and anterior cingulate cortex
(ACC) are the two main centers of information
processing, cognitive and affective functions, and
regulation in the brain, and are structurally and
functionally connected to each other. Thus, the
connections between these regions was investigated
longitudinally.
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