Abstract #1407
An 8 month longitudinal study of T1 measures in MS patients using 3D MPnRAGE
Steven R Kecskemeti 1 , Andrew L Alexander 1,2 , and Aaron S Field 3
1
Waisman Center, University of Wisconsin,
Madison, Wisconsin, United States,
2
Medical
Physics, University of Wisconsin, Madison, Wisconsin,
United States,
3
Radioilogy,
University of Wisconsin, Madison, Wisconsin, United
States
This study presents a longitudinal study of 8 monthly
scans using 3D MPnRAGE of two volunteers with multiple
sclerosis. T1 maps of normal appearing white matter and
gray matter are highly reproducible as determined by the
temporal coefficient of variation. Coefficient of
variation for a WM lesion that appeared during the study
was approximately 8x larger than normal appearing WM,
suggesting coefficient of variation of T1 across time
may be a useful biomarker to describe progression or
treatment of MS.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
