Abstract #1405
Quantitative Susceptibility Mapping (QSM) indicates disturbed brain iron homeostasis in Neuromyelitis Optica
Thomas Martin Doring 1 , Vanessa Granado 2 , Gustavo Tukamoto 3 , Fernanda Rueda 3 , Andreas Deistung 4 , Juergen Reichenbach 5 , Emerson Gasparetto 6 , and Ferdinand Schweser 7
1
Radiodiagnostic Imaging, DASA, Rio de
janeiro, Rio de Janeiro, Brazil,
2
Radiologia,
CDPI, Rio de Janeiro, Brazil,
3
CDPI,
Rio de Janeiro, Brazil,
4
Medical
Physics, Uni Jena, Thueringen, Germany,
5
Medical
Physics Group, Uni Jena, Thueringen, Germany,
6
DASA,
Rio de Janeiro, Brazil,
7
CTRC
and Buffalo Neuroimaging Analysis Center, University of
NY, Buffalo NY, United States
Neuromyelitis optica (NMO) is a severe, inflammatory
demyelinating disease that typically affects optic nerve
and spinal cord. The purpose of the current study was to
investigate brain iron and myelin in NMO patients using
two quantitative imaging techniques, R2* mapping and the
relatively new Quantitative Susceptibility Mapping.
Advanced neuroimaging techniques have recently been
explored to discover new diagnostic criteria to detect
NMO and to overcome the problem to distinguish this
disease from MS.
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