Abstract #1288
Subcortical rather than cortical changes mediate the clinical profile on ADHD boys at an earlier stage
Qi Liu 1 , Lizhou Chen 1 , Ying Chen 2 , Xinyu Hu 1 , Ming Zhou 1 , Fei Li 1 , Lanting Guo 2 , Qiyong Gong 1 , and Xiaoqi Huang 1
1
Huaxi MR Research Center (HMRRC), Department
of Radiology, West China Hospital of Sichuan University,
Chengdu, Sichuan, China,
2
Deptmeny
of Psychiatry, West China Hospital of Sichuan
University, P.R.China, Chengdu, Sichuan, China
Attention-deficit/hyperactivity disorder (ADHD) is one
of the most common neurodevelopmental disorders in
childhood. The present study aimed to explore the brain
structural changes between medicated-nave male ADHD and
healthy controls. Finally, we found that subcortical
volumes of bilateral putamen and amygdala were smaller
in ADHD group, and those changes were significantly
correlated with clinical measurements for behavioral
problems and some specific executive domains. This
suggested that putamen and amygdala may play key roles
in ADHD.
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