Abstract #1266
Diffusion MRI identifies enhanced connection of neural pathways in toddlers with Autism Spectrum Disorder
J. Mitra 1 , E. Conti 2,3 , K-K. Shen 1 , J. Fripp 1 , O. Salvado 1 , S. Calderoni 2 , A. Guzzetta 2,3 , and S. Rose 1
1
Australian e-Health & Research Centre, CSIRO
Digital Productivity Flagship, Herston, QLD, Australia,
2
Dept.
of Developmental Neuroscience, Stella Maris Scientific
Institute, Pisa, Italy,
3
University
of Pisa, Pisa, Italy
Autism Spectrum Disorder (ASD) is a heterogeneous group
of neuro-developmental diseases and is characterized by
impairment in socio-communicative abilities, as well as
restricted and stereotyped behaviours. There is a
growing interest in identifying structural and
functional neuro-anatomical correlates of the disorder
that has the potential to predict early behavioural
assessment impacting tailored rehabilitation
intervention. In this study we analyse the diffusion MRI
of ASD and developmental delay (DD) infants below 36
months of age and compare the differences in neural
pathways using network based statistics. Further we
analyse the asymmetry between the two cohorts from the
obtained neural pathways.
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