Abstract #1264
MRI based semi-automatic volumetric measurements of the fetal brain
Daphna Link 1,2 , Michael Braginsky 3 , Leo Joskowicz 3 , Liat Ben Sira 4 , Gustavo Malinger 5 , Ariel Many 6 , and Dafna Ben Bashat 1,7
1
Functional Brain Center, The Wohl Institute
for Advanced Imaging, Tel Aviv Sourasky Medical Center,
Tel Aviv, Israel,
2
Sackler
Faculty of Medicine, Tel Aviv University, Tel Aviv,
Israel,
3
School
of Engineering and Computer Science, The Hebrew
University of Jerusalem, Jerusalem, Israel,
4
Division
of Pediatric Radiology, Tel Aviv Sourasky Medical
Center, Tel Aviv, Israel,
5
Obstetrics
and Gynecology US Unit, Tel Aviv Sourasky Medical
Center, Tel Aviv, Israel,
6
Department
of Obstetrics and Gynecology, Lis Maternity Hospital,
Tel Aviv Sourasky Medical Center, Tel Aviv, Israel,
7
Sackler
Faculty of Medicine and Sagol school of neuroscience,
Tel Aviv University, Tel Aviv, Israel
Accurate volumetric measurements of the fetal brain are
clinically important to assess fetal development. In
this study a novel semi-automatic segmentation method
was used to extract and measure fetal brain volumes from
high resolution MR images in fifteen typically developed
and seven IUGR fetuses, and tested against manual
segmentation validated by a senior neuro-radiologist. A
good correlation was obtained between the algorithm and
manual segmentation results (mean: 4.77% volume
difference; 18.13% volume overlap difference) and with
significantly reduced time taken (~99% less than manual
segmentation). Furthermore, significant differences were
detected between brain volumes of normal and IUGR
fetuses.
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