Abstract #1234
Time-dependent diffusion as a biomarker for rotator cuff atrophy
Gregory Lemberskiy 1,2 , Dmitry Novikov 1 , Mary Bruno 1 , Els Fieremans 1 , and Soterios Gyftopoulos 1
1
Bernard and Irene Schwartz Center for
Biomedical Imaging, Department of Radiology, New York
University School of Medicine, New York, NY, United
States,
2
Sackler
Institute of Graduate Biomedical Sciences, New York
University School of Medicine, New York, NY, United
States
We show that modeling myofiber diameter using time
dependent diffusion is feasible in the rotator cuff by
comparing the diameters of the infraspinatus and
supraspinatus across 10 shoulders. Fiber diameters in 2
clinical patients with full thickness tears were
quantified longitudinally within 2 weeks prior to
surgery and 3 months after surgery. Our method showed a
systematic drop in fiber diameter after 3 months
indicating that the model could serve as a biomarker for
atrophy consequently and surgical outcome.
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