Abstract #1181
Cartilage evaluation by gagCEST at 3 Tesla after arthroscopic partial meniscectomy
Olgica Zaric 1 , Pavol Szomolanyi 1 , Vladimir Mlynarik 1 , Vladimir Juras 1 , and Siegfried Trattnig 1
1
High Field MR Center, Department of
Biomedical Imaging and Image-guided Therapy, Medical
University of Vienna, Vienna, Austria
Recent studies has shown that removal of the entire
meniscus can lead to the development of osteoarthritis
in a high proportion of cases in a long run. This study
used 3 Tesla gagCEST MRI for early postoperative
quantitative evaluation of biochemical changes in
articular cartilage adjacent to operated meniscus after
PMA. We observed lower gagCEST values in cartilage
adjacent to the operated meniscus than in the healthy
cartilage within the same subject. This loss in GAG
content could be biomarker of early cartilage
degeneration. gagCEST at 3 Tesla has great potential in
the investigation of early signs of osteoarthritis.
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