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Abstract #1130

Assessment of Tumor Morphology on Diffusion-Weighted Breast MRI: Diagnostic Value of Reduced FOV High Resolution Diffusion-Weighted Imaging

Maarten W. Barentsz 1 , Valentina Taviani 2 , Jung M. Chang 3 , Debra M. Ikeda 2 , Kanae K. Myiake 4 , Suchandrima Banerjee 5 , Maurice A.A.J. van den Bosch 1 , Brian A. Hargreaves 2 , and Bruce L. Daniel 2

1 Radiology, University Medical Center Utrecht, Utrecht, Netherlands, 2 Radiology, Stanford University, Stanford, CA, United States, 3 Radiology, Seul National University Hospital, Seul, Korea, 4 Diagnostic Imaging and Nuclear Medicine, Kyoto University Hospital, Kyoto, Japan, 5 Global Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States

The diagnostic value of reduced FOV (r-FOV) high resolution diffusion-weighted imaging (DWI) in discriminating between benign and malignant breast lesions was assessed with respect to conventional, bilateral (bil) DWI and contrast-enhanced (CE) MRI. The discriminatory ability of r-FOV based on ADC was similar to bil-DWI. The area under the receiver operating characteristics for the predictive value of lesion shape and BI-RADS classification was higher when r-FOV DWI was used instead of bil-DWI. CE-MRI alone had a higher predictive value for malignancies than both r-FOV and bil-DWI. High-resolution DWI of targeted lesions allowed more accurate evaluation of tumor morphology than bil-DWI.

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