Abstract #1100
Intravoxel Incoherent Motion Diffusion Weighted Imaging(IVIM-DWI) on a mouse xenografts model of human nasopharyngeal carcinoma CNE-2 cell line: A preliminary study on 3.0T MRI
Youping Xiao 1 , Yunbin Chen 1 , Jianji Pan 2 , Ying Chen 1 , Yiqi Yao 1 , Xiang Zheng 1 , Xiangyi Liu 1 , Dechun Zheng 1 , and Weibo Chen 3
1
Radiology, Fujian Provincial Cancer
Hospital, Fuzhou, Fujian, China,
2
Radiation
Oncology, Fujian Provincial Cancer Hospital, Fuzhou,
Fujian, China,
3
Philips
Healthcare, Shanghai, China
The results of this present study shows that intravoxel
incoherent montion diffusion weighted imaging(IVIM-DWI)
derived parameters present a good producibility and
feasibility on xenografts of human nasopharyngeal
carcinoma(NPC) cell line CNE-2 which have a significant
higher D(pure diffusion coefficient) and a lower
f(fraction of perfusion) parameter. It is indicated that
IVIM-DWI would be valuable in helping evaluate the
micro-environment characteristic of diffusion and
perfusion in NPC's xenograft, especially during the
process of chemoradiotherapy.
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