Abstract #1092
Monitoring cancer treatment: quantitative MRI of tumor micro-structure and metabolism with chemical exchange saturation transfer and diffusion weighted MRI
Rozhin Yousefi 1 , Xiaoyong Huang 2 , Stanley K. Liu 2 , and Greg J. Stanisz 1,2
1
Medical Biophysics, University of Toronto,
Toronto, Ontario, Canada,
2
Sunnybrook
Research Institute, Toronto, Ontario, Canada
In recent years, the number of available treatment
modalities for cancer has increased significantly while
their effectiveness remains uncertain. Finding a
non-invasive imaging method to provide early assessment
of tumor response to therapy will significantly enhance
treatment outcome. Our proposed method is to apply
quantitative MRI (qMRI) to evaluate tumor
micro-structure and metabolism during treatment using
two MRI techniques: chemical exchange saturation
transfer (CEST) and diffusion weighted MRI (DW-MRI). In
vivo experimental results showed significant differences
in qMRI measurements of tumors including apparent
diffusion coefficient (ADC) and amine CEST peak, before
and after treatment.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
