Abstract #1003
Multi-center Evaluation of Accelerated 3D Magnetic Resonance Perfusion Imaging for Assessing Myocardial Ischemic Burden to Detect Coronary Heart Disease
Robert Manka 1,2 , Lukas Wissmann 2 , Rolf Gebker 3 , Roy Jogiya 4 , Manish Motwani 5 , Michael Frick 6 , Sebastian Reinartz 6 , Bernhard Schnackenburg 3 , Markus Niemann 2 , Alexander Gotschy 1 , Christiane Kuhl 6 , Eike Nagel 4 , Eckart Fleck 3 , Thomas F Luescher 1 , Sven Plein 5 , and Sebastian Kozerke 2,4
1
University Hospital Zurich, Zurich,
Switzerland,
2
University
and ETH Zurich, Zurich, Switzerland,
3
German
Heart Institute, Berlin, Germany,
4
King's
College London, United Kingdom,
5
University
of Leeds, United Kingdom,
6
University
Hospital Aachen, Germany
In this multi-center study the diagnostic performance of
accelerated 3D myocardial perfusion imaging to detect
functionally relevant coronary heart disease (CAD) was
assessed relative to the invasive fractional flow
reserve (FFR) reference standard. The sensitivity and
specificity of myocardial ischemic burden as a metric to
assess severity of CAD were 84.7% and 92.3% relative to
the FFR reference confirming excellent diagnostic yield
of 3D perfusion imaging in a multi-center setting.
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