Abstract #0997
Contrast Generation with a Novel Adiabatic On-Resonance Magnetization Transfer Preparation (MT-Prep)
Wolfgang G Rehwald 1 , David C Wendell 2 , Elizabeth R Jenista 2 , Han W Kim 2 , Enn-Ling Chen 2 , Igor Klem 2 , and Raymond J Kim 2
1
Siemens Healthcare, Durham, NC, United
States,
2
Cardiology,
Duke University Medical School, Durham, North Carolina,
United States
Magnetization transfer contrast could be a clinically
and technically advantageous alternative to T2-contrast.
It would be useful for imaging edema and creating
tissue-blood contrast, if its energy and power
requirements did not exceed the capabilities of most
clinical MRI scanners. To address this issue, we
designed an efficient adiabatic on-resonance MT module
that imparts significant MT-weighting while remaining
within the energy and power constraints of most clinical
MRI scanners. In ten cardiac patients, we compared this
module to standard high-power off-resonance MT
preparation and established its image quality and
contrast equivalence while only requiring a fraction of
its energy.
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