Abstract #0976
Bicuspid Valve Morphology Determines the Position of Elevated Velocity and WSS: 4D Flow MRI in 202 Subjects
Pim van Ooij 1,2 , Ian G Murphy 2 , Alexander L Powell 2 , Maria Carr 2 , Wouter V Potters 1 , Colleen Clennon 3 , Jeremy D Collins 2 , James C Carr 2 , S Chris Malaisrie 4 , Patrick M McCarthy 3 , Michael Markl 2,5 , and Alex J Barker 2
1
Radiology, Academic Medical Center,
Amsterdam, Netherlands,
2
Radiology,
Northwestern University, Chicago, IL, United States,
3
Division
of Cardiac Surgery, Northwestern University, Chicago,
IL, United States,
4
Medicine-Cardiology,
Northwestern University, Chicago, IL, United States,
5
Northwestern
University, Biomedical Engineering, Chicago, IL, United
States
Bicuspid valve (BAV) patients are known to express two
different types of aortic dilation: 1) with involvement
of the root or 2) dilation of the distal aorta. In this
4D flow MRI study, 140 BAV patients are compared with 60
volunteers. With advanced postprocessing techniques
(cohort-averaged and P-value maps) it is shown that
differences in BAV opening lead to differences in
velocity and WSS expression that may be related to the
different types of dilation.
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