Abstract #0797
An extensible methodology for creating realistic anthropomorphic digital phantoms for quantitative imaging algorithm comparisons and validation
Ryan J Bosca 1 and Edward F Jackson 1
1
Medical Physics, University of Wisconsin -
Madison, Madison, WI, United States
Increasing interest in and use of quantitative imaging
biomarkers in clinical research and clinical practice
necessitates careful assessment and mitigation of bias
and variance associated with the acquisition and image
analysis techniques, especially in the context of
spatially heterogeneous processes. In this work, we
report an extensible methodology for creating an
anthropomorphic digital reference object (DRO) with a
synthetic tumor to evaluate quantitative imaging
algorithms using a realistic data analysis scenario with
known ground truth. Such a realistic DRO facilitates
quantitative imaging biomarker algorithm comparisons and
validation.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here