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Abstract #0766

High resolution spectroscopic imaging with ultra short TE in patients with multiple sclerosis and brain tumors at 7T

Gilbert Hangel 1 , Bernhard Strasser 1 , Michal Povaan 1 , Stephan Gruber 1 , Marek Chmelik 1 , Georg Widhalm 2 , Engelbert Knosp 2 , Assunta Dal-Bianco 3 , Fritz Leutmezer 3 , Siegfried Trattnig 1 , and Wolfgang Bogner 1

1 MCRE, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Wien, Vienna, Austria, 2 Department of Neurosurgery, Medical University of Vienna, Wien, Vienna, Austria, 3 Department of Neurology, Medical University of Vienna, Wien, Vienna, Austria

This work presents the application of single- and multi-slice accelerated high resolution FID-based spectroscopic imaging sequences with ultra-short TE in patients with multiple sclerosis and brain tumors at 7T. Using the parallel imaging method CAIPIRINHA for 2D and 3D acceleration, the measurement time for a single slice 6464 matrix could be reduced to 6:00 minutes, as well as 22:35 minutes for a 64644 matrix, allowing the inclusion into a standard imaging protocol. The acquired metabolic maps correlated well with lesions found on anatomical images, indicating a possible future use in diagnostics for multiple sclerosis and brain tumors.

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