Abstract #0728
Stretched-exponential model DWI (SEM-DWI) as a potential imaging biomarker in grading gliomas and assessment of proliferative activity
Jingjing Jiang 1 and Wenzhen Zhu 1
1
Tongji hospital, tongji medical college,
huazhong university of science and technology, Wuhan,
Hubei, China
Diffusion wighted imaging (DWI) is one of the advanced
neuroimaging techniques in the evaluation of brain
tumors. Stretched exponential model DWI (SEM-DWI) is one
of them which can properly describe the signal intensity
decay when b-factor exceeds 1000 s/mm2. Proliferating
cell nuclear antigen (PCNA) and Ki-67 are two of the
common nuclear markers in proliferation activity
evaluation. In this study, we will assess the
feasibility of SEM-DWI in grading gliomas and to find
the correlation between DWI parameters and PCNA and
Ki-67 labeling index (LI) thus to evaluate DWI as a
noninvasive technique for evaluating the proliferative
characteristics of gliomas.
This abstract and the presentation materials are available to members only;
a login is required.
Join Here
