Abstract #0624
8-channel double tuned 13 C- 1 H transceiver phased array for 13 C MRS in human brain at 7T
Guillaume Donati 1 , Ozlem Ipek 2 , Eulalia Sers Roig 1 , and Rolf Gruetter 1,3
1
Laboratory of Functional and Metabolic
Imaging, cole Polytechnique Fdrale de Lausanne,
Lausanne, Vaud, Switzerland,
2
Centre
d'Imagerie Biomdicale, cole Polytechnique Fdrale de
Lausanne, Lausanne, Vaud, Switzerland,
3
Department
of Radiology, Universities of Lausanne and Geneva,
Lausanne, Geneva, Switzerland
The main drawback of
13
C-MRS
is the low sensitivity, which makes
13
C
detection difficult. In addition, the
13
C-
1
H
hetero-nuclear J coupling necessitates double-tuned
13
C-
1
H
coils for proton decoupling during
13
C
signal acquisition. Array coils provide a high
sensitivity over a large field-of-view. In this study, a
four channel
13
C-four
channel
1
H
transceiver array coil for direct
13
C-MRS
in human brain at 7T was built. EM simulations show a
fourfold improvement of B
1
+
/√SAR
10g,max
compared
to a linear
13
C-quadrature
1
H
coil.
1
H-decoupled
13
C
MRS spectra were acquired in vitro, demonstrating the
feasibility of an eight channel double-tuned transceiver
13
C-
1
H
array at 7T.
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