Abstract #0561
Large coverage HOmologous Black-Bright blood Interleaved imaging sequence (LaHOBBI) for 3D dynamic contrast enhanced MRI of vessel wall
Haikun Qi 1 , Shuo Chen 1 , Zechen Zhou 1 , Jinnan Wang 2 , Peter Koken 3 , Niranjan Balu 4 , and Huijun Chen 1
1
Department of Biomedical Engineering, School
of Medicine, Tsinghua University, Beijing, Beijing,
China,
2
Philips
Research North America, Briarcliff Manor, New York,
United States,
3
Innovative
Technologies, Research Laboratories, Philips
Technologies GmbH, Hamburg, Germany,
4
Radiology,
University of Washington, Seattle, WA, United States
Dynamic contrast enhanced (DCE) MRI is important in
quantifying inflammatory features of atherosclerotic
plaque, and interleaved black-bright imaging technique
is essential for quantitative vessel wall DCE analysis.
In this study, a Large coverage HOmologous black-bright
blood Interleaved imaging sequence (LaHOBBI) for vessel
wall DCE MRI was proposed. The feasibility of the
conducting the proposed sequence was demonstrated by in
vivo experiment on carotid. The LaHOBBI sequence enables
3D large coverage, high spatial resolution vessel wall
DCE imaging and 2D high temporal bright blood imaging
for accurate AIF extraction, which ensures the
quantitative DCE analysis and coverage of
atherosclerotic plaque.
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