Abstract #0557
Time-efficient whole-heart coronary plaque characterization with simultaneously acquired MRA
Yibin Xie 1,2 , Young Jin Kim 3 , Jianing Pang 1 , Jung-Sun Kim 4 , Qi Yang 1 , Zhaoyang Fan 1 , Hyuk-Jae Chang 4 , and Debiao Li 1
1
Biomedical Imaging Research Institute,
Cedars-Sinai Medical Center, Los Angeles, California,
United States,
2
University
of California, Los Angeles, Los Angeles, California,
United States,
3
Department
of Radiology, Severance Hospital, Yonsei University
College of Medicine, Seoul, Korea,
4
Division
of Cardiology, Yonsei Cardiovascular Center, Yonsei
University College of Medicine, Seoul, Korea
Recently T1-weighted MRI with or without contrast
enhancement has been used for characterizing coronary
plaques showing promising prognostic value for coronary
events. However the drawbacks of current protocols using
conventional Cartesian acquisition and respiratory
gating may hinder the clinical application of this
technique due to limited anatomical coverage, low
anisotropic resolution and the requirement of a separate
bright-blood MRA scan. We developed a time-efficient
protocol based on 3DPR with simultaneously acquired MRA
to address these limitations and performed preliminary
clinical validation on 11 CAD patients using CT angio,
X-ray angio, and intracoronary OCT as reference.
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