Abstract #0534
Non-Contrast Pulmonary Perfusion using pseudo-Continuous Arterial Spin Labeling of the Inferior Vena Cava
Joshua S. Greer 1,2 , Yue Zhang 2 , Ivan Pedrosa 2,3 , and Ananth J. Madhuranthakam 2,3
1
Bioengineering, UT Dallas, Dallas, TX,
United States,
2
Radiology,
UT Southwestern Medical Center, Dallas, TX, United
States,
3
Advanced
Imaging Research Center, UT Southwestern Medical Center,
Dallas, TX, United States
Recently, pseudo-continuous ASL (pCASL) has been
successfully applied to study cerebral and renal
perfusion by labeling the carotid arteries and abdominal
aorta. The high blood velocity in these anatomies
enabled high labeling efficiency. However, the extension
of pCASL to study pulmonary perfusion has been
non-trivial due to the complex anatomy of the lungs. In
this work, we demonstrate pulmonary perfusion using
pCASL, specifically targeting the inferior vena cava and
optimizing the labeling parameters to achieve high
labeling efficiency. This provided higher SNR, reduced
pulmonary vasculature signal and more homogeneous
perfusion compared to the established pulsed ASL
approach (e.g. 2D FAIRER).
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