Abstract #0501
Actual Flip Angle Imaging to Improve T1 Measurement for Short T2 Tissues
Misung Han 1 , Peder EZ Larson 1 , Roland Krug 1 , and Viola Rieke 1
1
Radiology and Biomedical Imaging, University
of California, San Francisco, San Francisco, CA, United
States
A variable flip angle method is a rapid T
1
mapping
method by exploiting steady-state signals at multiple
flip angles. When combined with ultrashort echo-time
imaging, T
1
measurement
for short T
2
* tissues is also possible.
However, flip angle errors due to miscalibration or B
1
inhomogeneities,
and T
2
* relaxation effects during RF
excitation can degrade the accuracy of T
1
quantification.
In this work, we propose the use of the actual flip
imaging technique to correct flip angles to improve T
1
measurement
for short T
2
tissues.
Ex vivo study on bovine cortical bone and in vivo study
on the Achilles tendon are presented.
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