Abstract #0390
Non-Invasive Characterization and Staging of Portal Hypertension using 4D Flow MRI
Alejandro Roldn-Alzate 1 , Adnan Said 2 , Camilo Campo 1 , Kevin M Johnson 3 , Christopher J Francois 1 , Oliver Wieben 1,3 , and Scott B Reeder 1,3
1
Radiology, University of Wisconsin -
Madison, Madison, WI, United States,
2
Hepatology,
University of Wisconsin - Madison, Madison, WI, United
States,
3
Medical Physics, University of
Wisconsin - Madison, Madison, WI, United States
The purpose of this study was to evaluate 4D flow MRI as
non-invasive method for characterizing and staging
patients with portal hypertension. Nineteen patients
with cirrhosis and suspected portal hypertension were
studied. Significant increase in portal venous flow and
no significant increase in azygos flow were seen in
response to meal challenge. Good correlation was
observed between baseline azygos flow and the Child-Pugh
score as well as between portal venous shunt fraction at
baseline and Child-Pugh score. The ability to
non-invasively quantify hemodynamic changes not only in
normal vessels but also in collateral circulation
demonstrates that 4D flow MRI may be a suitable tool for
staging and monitoring treatment of patients with portal
hypertension.
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