Abstract #0284
Cortical Mapping of Magnetic Susceptibility and R2* reveals Insights into Tissue Composition
Andreas Deistung 1 , Andreas Schfer 2 , Ferdinand Schweser 3,4 , and Jrgen Rainer Reichenbach 1
1
Medical Physics Group, Institute of
Diagnostic and Interventional Radiology, Jena University
Hospital - Friedrich Schiller University Jena, Jena,
Germany,
2
Department of Neurophysics,
Max-Planck-Institute for Human Cognitive and Brain
Sciences, Leipzig, Germany,
3
Buffalo
Neuroimaging Analysis Center, Dept. of Neurology, School
of Medicine and Biomedical Sciences, State University of
New York at Buffalo, Buffalo, NY, United States,
4
MRI
Molecular and Translational Imaging Center Institution,
Buffalo CTRC, State University of New York at Buffalo,
Buffalo, NY, United States
We investigated the spatial distribution of both
magnetic susceptibility and R2* across the cerebral
cortex in vivo. We observed substantial variations of
magnetic susceptibility and R2* across the cortical
surface. Certain regions of magnetic susceptibility and
R2* coincided with the boundaries of the probabilistic
Brodmann atlas and other regions exhibited a
heterogeneous distribution within the specific Brodmann
area. In conclusion, cortical mapping of R2* and
magnetic susceptibility reveals insights into tissue
composition across the cerebral cortex and may be
instrumental for understanding the relationship between
tissue composition and functional roles of cortical gray
matter.
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