Abstract #0201
GABA concentration in the superior temporal gyrus predicts gamma-band oscillations and multisensory perception
Ralf Mekle 1 , Johanna Balz 2 , Julian Keil 2 , Yadira Roa-Romero 2 , Semiha Aydin 1 , Florian Schubert 1 , Bernd Ittermann 1 , Juergen Gallinat 3 , and Daniel Senkowski 2
1
Medical Physics, Physikalisch-Technische
Bundesanstalt, Berlin, Germany,
2
Department
of Psychiatry and Psychotherapy,
Charit-Universittsmedizin, Berlin, Germany,
3
Department
of Psychiatry and Psychotherapy, University Hospital
Hamburg-Eppendorf, Hamburg, Germany
The integration of different sensory streams into a
coherent, conscious percept is required for multisensory
perception, where in human brain the superior temporal
gyrus (STG) plays an important role. In this combined
MRS-EEG study, the sound-induced flash illusion (SIFI)
paradigm was applied to test the hypotheses that the
GABA concentration in the STG predicts multisensory
perception at the behavioral level and gamma-band
activity during SIFI. MRS data were acquired using
MEGA-PRESS at 3T, and EEG signals were recorded for 40
subjects. The hypotheses were confirmed, and a tight
triangular relationship between GABA concentration,
gamma-band oscillations, and multisensory perception was
found.
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