Abstract #0136
Characterizing cortical responses to the stimulation of single mechanoreceptive afferents using fMRI at 7 T
Rosa Maria Sanchez Panchuelo 1 , Rochelle Ackerley 2 , Paul Glover 1 , Richard Bowtell 1 , Francis McGlone 3 , Johan Wessberg 2 , and Susan Francis 1
1
University of Nottingham, Nottingham, United
Kingdom,
2
University
of Gothenburg, Gothenburg, Sweden,
3
Liverpool
Johns Moore University, Liverpool, United Kingdom
We successfully performed microstimulation of single
afferents in the environment of an ultra-high field (7T)
MR scanner and collected high resolution fMRI data
depicting the response to intraneural microstimulation
(INMS). fMRI data were acquired during INMS of 11
different afferents across four subjects. We compare the
cortical responses elicited by INMS of single afferents
with those produced by mechanical stimulation of each
afferents receptive field. We show that INMS and
vibrotactile stimulation engage sensory related brain
areas, and that INMS activates additional brain
networks. INMS responses were localized within the
expected area of digit representation in primary
somatosensory cortex.
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