Abstract #0034
Automatic and Quantitative Assessment of Total and Regional Muscle Tissue Volume using Multi-Atlas Segmentation
Anette Karlsson 1,2 , Johannes Rosander 3 , Joakim Tallberg 2 , Anders Grnqvist 2,4 , Magnus Borga 1,2 , and Olof Dahlqvist Leinhard 2,5
1
Department of Biomedical Engineering (IMT),
Linkping University, Linkping, Sweden, Sweden,
2
Center
for Medical Image Science and Visualization (CMIV),
Linkping University, Linkping, Sweden,
3
Advanced
MR Analytics (AMRA) AB, Linkping, Sweden,
4
Department
of Radiation Physics and Department of Medical and
Health Sciences, Linkping University, Linkping,
Sweden,
5
Department
of Medical and Health Sciences (IMH), Linkping
University, Linkping, Sweden
The purpose is to develop and demonstrate a rapid
whole-body MRI method for automatic quantification of
total and regional lean skeletal muscle volume.
Quantitative water and fat separated image volumes of
the whole body are manually segmented and used as
atlases. The atlases are non-rigidly registered onto to
a new image volume and the muscle groups are classified
using a voting scheme. A leave-one-out approach with
subjects scanned in a 1.5 T and a 3.0 T scanner is used
for validation. The method quantifies the whole-body
skeletal muscle volumes and the volumes of separate
muscle groups independently of image resolution.
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