Abstract #4695
Age-Dependent Changes in the Histograms of ADC Values
Uwe Klose 1 , Marion Batra 1 , and Thomas Ngele 1
1
Department of Diagnostic and Interventional
Neuroradiology, University Hospital of Tbingen,
Tbingen, Germany
Readout-segmented EPI (rs-EPI) sequences were used in in
clinical routine examinations. Calculated ADC histograms
were were examined for the detection of of age-dependent
brain volume losses. 783 patient measurements were
performed with a 3T scanner. Data were checked visually
and 233 data-sets with pathologies were excluded. The
value of the relative number of pixels in the brain
compartment of the histogram (ADC-values lower than 1.15
10
-3
mm
2
/s)
of each subject was evaluated. The results for all
patients were drawn against age and fitted by a
polynomial. The decrease of the fitted curve was
stronger for men than for women.
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