Abstract #4660
Structural Covariance Brain Networks in Preterm and Term Neonates
Mengye Lyu 1,2 , Xianjun Li 1,3 , Jing Wang 1,3 , Ed X. Wu 2,4 , and Jian Yang 1,3
1
Department of Radiology, The First
Affiliated Hospital of Medical College, Xi'an Jiaotong
University, Xi'an, Shaanxi, China,
2
Laboratory
of Biomedical Imaging and Signal Processing, The
University of Hong Kong, Hong Kong SAR, China,
3
Department
of Biomedical Engineering, School of Life Science and
Technology, Xi'an Jiaotong University, Xi'an, Shaanxi,
China,
4
Department
of Electrical and Electronic Engineering, The University
of Hong Kong, Hong Kong SAR, China
This study investigated the structural covariance
networks of preterm and term neonatal brains. By
examining the global topological properties,
inter-hemispheric connections, and nodal centrality
shift, we characterized the distinct features of these
two networks. The preterm neonatal brains, compared with
term neonatal brains, contained fewer high degree nodes
and had lower global and local efficiency.
Inter-hemispheric connections in preterm neonatal brains
were significantly fewer than in term. Regions involved
with visual processing and emotion gained higher
centrality in the term neonatal brains. These findings
revealed the connectivity pattern with increasing
regional interaction and integration in early brain
development.
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