Abstract #4576
Brainstem Cerebral Blood Flow in Women with Poly-Cystic Ovary Syndrome (PCOS)
Esther A. H. Warnert 1 , Andrew Lansdown 2 , Kevin Murphy 1 , Judith E. Hall 3 , D. Aled Rees 2 , and Richard G. Wise 1
1
CUBRIC, School of Psychology, Cardiff
University, Cardiff, United Kingdom,
2
Centre
for Endocrine and Diabetes Sciences, Institute of
Experimental and Molecular Medicine, School of Medicine,
Cardiff University, United Kingdom,
3
Department
of Anaesthetics and Intensive Care Medicine, School of
Medicine, Cardiff University, United Kingdom
This abstract contains preliminary results of a clinical
study investigating brain function and physiology in
women suffering from Poly-Cystic Ovary Syndrome (PCOS).
Here, we focus on the brainstem (and the medulla in
particular), because of the recent finding that a
potential marker of PCOS is hyperactivity of the
sympathetic nervous system, in which nuclei in the
medulla play a central role. Arterial spin labelling is
used to assess differences in brainstem cerebral blood
flow between PCOS patients and healthy controls.
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